Article

Phenotypes associated with genetic determinants of type I interferon regulation in the UK Biobank: a protocol

2023-11-23

Abstract excerpt

<h4>Background: </h4> Type I interferons are cytokines involved in innate immunity against viruses. Genetic disorders of type I interferon regulation are associated with a range of autoimmune and cerebrovascular phenotypes. Carriers of pathogenic variants involved in genetic disorders of type I interferons are generally considered asymptomatic. Preliminary data suggests, however, that genetically determined dysreg...

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Literature Corpus work: 07041f9c-c3e3-562f-8590-55a92c965ed4
DOI: 10.12688/wellcomeopenres.20385.1

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