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Article

The competition between simple and complex evolutionary trajectories in asexual populations.

BMC evolutionary biology - 26 Mar 2015

Ochs Ian E, Desai Michael M

Abstract excerpt

BACKGROUND: On rugged fitness landscapes where sign epistasis is common, adaptation can often involve either individually beneficial "uphill" mutations or more complex mutational trajectories involving fitness valleys or plateaus. The dynamics of the evolutionary process determine the probability that evolution will take any specific path among a variety of competing possible trajectories. Understanding this...

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Share to Adaptation, Physiological
Share to Biological Evolution
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Models, Genetic

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Share to Reproduction, Asexual

Share to Selection, Genetic

Source

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Identifiers

PMID: 25881244
DOI: 10.1186/s12862-015-0334-0
PMCID: PMC4391547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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