Article
A copy number gain of the 6p arm is linked with advanced hepatocellular carcinoma: an array-based comparative genomic hybridization study.
The Journal of pathology - 1 Apr 2009
Chochi Yasuyo, Kawauchi Shigeto, Nakao Motonao, Furuya Tomoko, Hashimoto Kiichiro, Oga Atunori, Oka Masaaki, Sasaki Kohsuke
Abstract excerpt
In accordance with cancer progression, genomic aberrations accumulate in cancer cells in a stepwise fashion. However, whether there are genomic changes linked with tumour progression remains unclarified. The purpose of this study is to elucidate the relationship between genomic alterations and clinical stages in hepatocellular carcinoma (HCC). A technology of array-based CGH using DNA chips spotted with 1440 BAC...
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