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Article

Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes.

Gastroenterology - 1 Apr 2013

Sia Daniela, Hoshida Yujin, Villanueva Augusto, Roayaie Sasan, Ferrer Joana, Tabak Barbara, Peix Judit, Sole Manel, Tovar Victoria, Alsinet Clara, Cornella Helena, Klotzle Brandy, Fan Jian-Bing, Cotsoglou Christian, Thung Swan N, Fuster Josep, Waxman Samuel, Garcia-Valdecasas Juan Carlos, Bruix Jordi, Schwartz Myron E, Beroukhim Rameen, Mazzaferro Vincenzo, Llovet Josep M

Abstract excerpt

BACKGROUND & AIMS: Cholangiocarcinoma, the second most common liver cancer, can be classified as intrahepatic cholangiocarcinoma (ICC) or extrahepatic cholangiocarcinoma. We performed an integrative genomic analysis of ICC samples from a large series of patients. METHODS: We performed a gene expression profile, high-density single-nucleotide polymorphism array, and mutation analyses using formalin-fixed ICC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23295441
DOI: 10.1053/j.gastro.2013.01.001
PMCID: PMC3624083

Genes

BRAF
KRAS
MET
SAV1
STAT3

Provenance

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