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Article

A mouse model of Alzheimer's disease displays increased susceptibility to kindling and seizure-associated death.

Epilepsia - 1 Jun 2015

Chan Jianxiong, Jones Nigel C, Bush Ashley I, O'Brien Terence J, Kwan Patrick

Abstract excerpt

People with Alzheimer's disease (AD) are up to 10 times more likely to develop epilepsy than the age-matched general population. However, given that only a proportion of patients with AD develop epilepsy, it is likely that additional factors may be required for the epilepsy to emerge. This study aimed to better understand the relationship between AD pathology and seizure susceptibility. It also aimed to...

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PMID: 25879152
DOI: 10.1111/epi.12993

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