An Endothelial Cell-Specific Requirement for the <i>UL133-UL138</i> Locus of Human Cytomegalovirus for Efficient Virus Maturation

Abstract excerpt

Human cytomegalovirus (HCMV) infects a variety of cell types in humans, resulting in a varied pathogenesis in the immunocompromised host. Endothelial cells (ECs) are considered an important target of HCMV infection that may contribute to viral pathogenesis. Although the viral determinants important for entry into ECs are well defined, the molecular determinants regulating postentry tropism in ECs are not known....

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