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Article

Multifactor-dimensionality reduction reveals interaction of important gene variants involved in allergy.

International journal of immunogenetics - 1 Jun 2015

de Guia R M, Echavez M D J, Gaw E L C, Gomez M R R, Lopez K A J, Mendoza R C M, Rapsing J M C, Retreta D P, Tubog C M B, Ventolero M H, Yao C L, Ramos J D A

Abstract excerpt

Elevated IgE levels in the atopic triad of asthma, allergic rhinitis and atopic dermatitis is a multifactorial condition whose genetic component involves interaction of several gene loci. One hundred and two matched pairs of allergic and nonallergic individuals were phenotyped for total serum IgE level using enzyme-linked immunosorbent assay (ELISA). Atopic status was defined by serum IgE concentration ≥100 IU...

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Topics

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Share to Epistasis, Genetic
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypersensitivity, Immediate

Share to Immunoglobulin E

Share to Models, Genetic

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Source

Identifiers

PMID: 25876437
DOI: 10.1111/iji.12200

Genes

ADRB2

Variants

rs2243250

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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