Article
miR-145 Contributes to Hypertrophic Scarring of the Skin by Inducing Myofibroblast Activity.
Molecular medicine (Cambridge, Mass.) - 9 Apr 2015
Gras Christiane, Ratuszny Dominica, Hadamitzky Catarina, Zhang Haijiao, Blasczyk Rainer, Figueiredo Constança
Abstract excerpt
Hyperthrophic scarring of the skin is caused by excessive activity of skin myofibroblasts after wound healing and often leads to functional and/or aesthetic disturbance with significant impairment of patient quality of life. MicroRNA (miRNA) gene therapies have recently been proposed for complex processes such as fibrosis and scarring. In this study, we focused on the role of miR-145 in skin scarring and its...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.