Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA‐145‐5p regulates fibrotic features of recessive dystrophic epidermolysis bullosa skin fibroblasts

28 Feb 2019

Abstract excerpt

BACKGROUND: Recessive dystrophic epidermolysis bullosa (RDEB) is a skin fragility disorder caused by mutations in the COL7A1 gene encoding type VII collagen, a cutaneous basement membrane component essential for epidermal-dermal adhesion. Hallmarks of the disease are unremitting blistering and chronic wounds with severe inflammation and fibrosis. MicroRNAs (miRNAs) are post-transcriptional regulators of gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatological and Skeletal Disorders
Share to Hair Growth and Disorders
Share to Skin and Cellular Biology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30816994
DOI: 10.1111/bjd.17840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA‐145‐5p regulates fibrotic features of recessive dystrophic epidermolysis bullosa skin fibroblastsPMID 30816994Read ↗

Monozygotic twins discordant for recessive dystrophic epidermolysis bullosa phenotype highlight the role of TGF-β signalling in modifying disease severity.Semantic proximity Read ↗

Unravelling drivers of cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.Semantic proximity Read ↗

Impaired Wound Healing, Fibrosis, and Cancer: The Paradigm of Recessive Dystrophic Epidermolysis Bullosa.Semantic proximity Read ↗

Signatures of Dermal Fibroblasts from RDEB Pediatric Patients.Semantic proximity Read ↗

Inhibition of CUB and sushi multiple domains 1 (CSMD1) expression by miRNA-190a-3p enhances hypertrophic scar-derived fibroblast migration in vitroSemantic proximity Read ↗

Therapies for genetic extracellular matrix diseases of the skin.Semantic proximity Read ↗

Pathomechanisms of Altered Wound Healing in Recessive Dystrophic Epidermolysis Bullosa.Semantic proximity Read ↗

TGFβ-signaling in Squamous Cell Carcinoma Occurring in Recessive Dystrophic Epidermolysis BullosaSemantic proximity Read ↗

miR-145 Contributes to Hypertrophic Scarring of the Skin by Inducing Myofibroblast Activity.Semantic proximity Read ↗

miR-29 Regulates Type VII Collagen in Recessive Dystrophic Epidermolysis BullosaSemantic proximity Read ↗

Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: A gene expression studySemantic proximity Read ↗

Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis BullosaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.