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Article

Wnt/β-catenin pathway forms a negative feedback loop during TGF-β1 induced human normal skin fibroblast-to-myofibroblast transition.

Journal of dermatological science - 1 Jan 2012

Liu Jiaqi, Wang Yunchuan, Pan Qing, Su Yingjun, Zhang Zhanfeng, Han Juntao, Zhu Xiongxiang, Tang Chaowu, Hu Dahai

Abstract excerpt

BACKGROUND: Fibroblast-to-myofibroblast transition is a key event during wound healing and hypertrophic scar formation. Previous studies suggested Wnt/β-catenin signaling might be involved in the wound healing. However, its specific role in skin fibroblast-to-myofibroblast transition remains unclear. OBJECTIVE: To investigate the specific role of β-catenin during the transforming growth factor-β1 induced normal...

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Identifiers

PMID: 22041457
DOI: 10.1016/j.jdermsci.2011.09.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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