Article
Ski diminishes TGF-β1-induced myofibroblast phenotype via up-regulating Meox2 expression.
Experimental and molecular pathology - 1 Dec 2014
Chen Zhaowei, Li Wenjing, Ning Yan, Liu Tong, Shao Jingxiang, Wang Yaojun
Abstract excerpt
OBJECTIVE: The aim of the present work was to investigate the mechanism of transforming growth factor (TGF)-β1 and Sloan-Kettering Institute (Ski) in the pathogenesis of hypertrophic scars (HS). BACKGROUND: Wound healing is an inherent process, but the aberrant wound healing of skin injury may lead to HS. There has been growing evidence suggesting a role for TGF-β1 and Ski in the pathogenesis of fibrosis....
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