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Article

Lack of RNase H2 activity rescues HU-sensitivity of WEE1 deficient plants.

Plant signaling & behavior - 1 Jan 2015

Eekhout Thomas, Kalhorzadeh Pooneh, De Veylder Lieven

Abstract excerpt

Because of their sessile lifestyle, plants have developed extensive mechanisms to safeguard their genetic information from one generation to the next. The WEE1 kinase is one of the guardians of genome integrity, being important during S-phase progression under replication stress. Knock-out plants for WEE1 (WEE1(KO)) show a hypersensitive response when grown on replication-inhibiting drugs. Recently, we reported...

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Identifiers

PMID: 25875879
DOI: 10.1080/15592324.2014.1001226
PMCID: PMC4622661

Genes

WEE1

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