Article
The Arabidopsis thaliana checkpoint kinase WEE1 protects against premature vascular differentiation during replication stress.
The Plant cell - 1 Apr 2011
Cools Toon, Iantcheva Anelia, Weimer Annika K, Boens Shannah, Takahashi Naoki, Maes Sara, Van den Daele Hilde, Van Isterdael Gert, Schnittger Arp, De Veylder Lieven
Abstract excerpt
A sessile lifestyle forces plants to respond promptly to factors that affect their genomic integrity. Therefore, plants have developed checkpoint mechanisms to arrest cell cycle progression upon the occurrence of DNA stress, allowing the DNA to be repaired before onset of division. Previously, the WEE1 kinase had been demonstrated to be essential for delaying progression through the cell cycle in the presence of...
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