When one mutation is all it takes.

Abstract excerpt

In a recent issue of Nature Genetics, Andersson and colleagues report that MLL fusion alone may be sufficient to spawn an aggressive leukemia in infants. Some other pediatric cancers may share a similar, single, "big-hit" origin, possibly reflecting a critical developmental window of stem cell vu...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mutation
• Share to Myeloid-Lymphoid Leukemia Protein
• Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma