Article
Discovery analysis of TCGA data reveals association between germline genotype and survival in ovarian cancer patients.
PloS one - 1 Jan 2013
Braun Rosemary, Finney Richard, Yan Chunhua, Chen Qing-Rong, Hu Ying, Edmonson Michael, Meerzaman Daoud, Buetow Kenneth
Abstract excerpt
BACKGROUND: Ovarian cancer remains a significant public health burden, with the highest mortality rate of all the gynecological cancers. This is attributable to the late stage at which the majority of ovarian cancers are diagnosed, coupled with the low and variable response of advanced tumors to standard chemotherapies. To date, clinically useful predictors of treatment response remain lacking. Identifying the...
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