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Article

Alteration of major vault protein in human glioblastoma and its relation with EGFR and PTEN status.

Neuroscience - 25 Jun 2015

Navarro L, Gil-Benso R, Megías J, Muñoz-Hidalgo L, San-Miguel T, Callaghan R C, González-Darder J M, López-Ginés C, Cerdá-Nicolás M J

Abstract excerpt

Glioblastoma (GBM) is the most frequent and malignant primary brain tumor. Conventional therapy of surgical removal, radiation and chemotherapy is largely palliative. Major vault protein (MVP), the main component of the vault organelle has been associated with multidrug resistance by reducing cel...

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Topics

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Share to Brain Neoplasms
Share to Chromosomes, Human, Pair 7
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Glioblastoma

Share to PTEN Phosphohydrolase

Share to Statistics, Nonparametric

Share to Young Adult

Source

Identifiers

PMID: 25869624
DOI: 10.1016/j.neuroscience.2015.04.005

Genes

MVP
EGFR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25869624-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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