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Article

Cellular Levels of Signaling Factors Are Sensed by β-actin Alleles to Modulate Transcriptional Pulse Intensity.

Cell reports - 21 Apr 2015

Kalo Alon, Kanter Itamar, Shraga Amit, Sheinberger Jonathan, Tzemach Hadar, Kinor Noa, Singer Robert H, Lionnet Timothée, Shav-Tal Yaron

Abstract excerpt

The transcriptional response of β-actin to extra-cellular stimuli is a paradigm for transcription factor complex assembly and regulation. Serum induction leads to a precisely timed pulse of β-actin transcription in the cell population. Actin protein is proposed to be involved in this response, but it is not known whether cellular actin levels affect nuclear β-actin transcription. We perturbed the levels of key...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25865891
DOI: 10.1016/j.celrep.2015.03.039
PMCID: PMC4743029

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SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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