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Article

Repurposing of the antihistamine chlorcyclizine and related compounds for treatment of hepatitis C virus infection.

Science translational medicine - 8 Apr 2015

He Shanshan, Lin Billy, Chu Virginia, Hu Zongyi, Hu Xin, Xiao Jingbo, Wang Amy Q, Schweitzer Cameron J, Li Qisheng, Imamura Michio, Hiraga Nobuhiko, Southall Noel, Ferrer Marc, Zheng Wei, Chayama Kazuaki, Marugan Juan J, Liang T Jake

Abstract excerpt

Hepatitis C virus (HCV) infection affects an estimated 185 million people worldwide, with chronic infection often leading to liver cirrhosis and hepatocellular carcinoma. Although HCV is curable, there is an unmet need for the development of effective and affordable treatment options. Through a c...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25855495
DOI: 10.1126/scitranslmed.3010286
PMCID: PMC6420960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25855495-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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