Article
Association of TP53 PIN3 polymorphism with breast cancer in Moroccan population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2014
Marouf Chaymaa, Tazzite Amal, Diakité Brehima, Jouhadi Hassan, Benider Abdellatif, Nadifi Sellama
Abstract excerpt
TP53 is a tumor suppressor gene involved in cell cycle progression control, DNA damage repair, genomic stability, and apoptosis. Some polymorphisms in this gene have been associated with the development of a number of cancers including breast carcinoma. PIN3 Ins16bp polymorphism has been widely studied in different populations for an association with breast cancer risk. In most case-control studies, a duplicated...
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