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Article

The GAB2 and BDNF polymorphisms and the risk for late-onset Alzheimer's disease in an elderly Brazilian sample.

International psychogeriatrics - 1 Oct 2015

Vieira Renalice Neves, Magalhães Joalce Dornelas, Sant'Anna Jemima, Moriguti Mateus Massao, de Paula Jonas Jardim, Cintra Marco Túlio Gualberto, de Miranda Débora Marques, De Marco Luiz, de Moraes Edgar Nunes, Romano-Silva Marco Aurélio, Bicalho Maria Aparecida Camargos

Abstract excerpt

BACKGROUND: Evidences suggest that GAB2 and BDNF genes may be associated with Alzheimer's disease (AD). We aimed to investigate the GAB2 rs2373115 and BDNF rs6265 polymorphisms and the risk of AD in a Brazilian sample. METHODS: 269 AD patients and 114 controls were genotyped with Real-time PCR. Multifactor dimensionality reduction (MDR) was employed to explore the effects of gene-gene interactions. RESULTS: GAB2...

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Source

Identifiers

PMID: 25853819
DOI: 10.1017/S1041610215000514

Genes

BDNF
APOE
GAB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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