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Article

Brain-derived neurotrophic factor gene variants and Alzheimer disease: an association study in an Alzheimer disease Italian population.

Rejuvenation research - 1 Feb 2013

Boiocchi Chiara, Maggioli Elisa, Zorzetto Michele, Sinforiani Elena, Cereda Cristina, Ricevuti Giovanni, Cuccia Mariaclara

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) promotes neuronal survival during development and protects neurons from insults of various kinds. Changes in production of BDNF have been reported in differing neurodegenerative pathologies and, in particular, in Alzheimer disease (AD). We studied 200 AD patients and 408 healthy controls for BDNF Val66Met(G196A) polymorphism, 200AD and 384 healthy controls for BDNF 270 C/T...

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Identifiers

PMID: 23215636
DOI: 10.1089/rej.2012.1381

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BDNF

Variants

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