The Molecular Architecture and Mode of Action of Clostridium perfringens ε-Toxin

Abstract excerpt

ε-toxin has long been associated with a severe enterotoxaemia of livestock animals, and more recently, was proposed to play a role in the etiology of multiple sclerosis in humans. The remarkable potency of the toxin has intrigued researchers for many decades, who suggested that this indicated an enzymatic mode of action. Recently, there have been major breakthroughs by finding that it is a pore-forming toxin...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Clostridium difficile and Clostridium perfringens research
• Share to Pharmacological Effects of Natural Compounds
• Share to Toxin Mechanisms and Immunotoxins