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Article

Maternal Stress Induces Epigenetic Signatures of Psychiatric and Neurological Diseases in the Offspring

22 Feb 2013

Abstract excerpt

The gestational state is a period of particular vulnerability to diseases that affect maternal and fetal health. Stress during gestation may represent a powerful influence on maternal mental health and offspring brain plasticity and development. Here we show that the fetal transcriptome, through microRNA (miRNA) regulation, responds to prenatal stress in association with epigenetic signatures of psychiatric and...

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Identifiers

PMID: 23451123
DOI: 10.1371/journal.pone.0056967

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