Article
Multivariate analysis of subjective responses to d-amphetamine in healthy volunteers finds novel genetic pathway associations.
Psychopharmacology - 1 Aug 2015
Yarosh Haley L, Meda Shashwath A, de Wit Harriet, Hart Amy B, Pearlson Godfrey D
Abstract excerpt
RATIONALE: Researchers studying behavioral and physiologic effects of d-amphetamine have explored individual response differences to the drug. Concurrently, genome-wide analyses have identified several single-nucleotide polymorphisms (SNPs) associated with these traits. Univariate methods can identify SNPs associated with behavioral and physiological traits, but multivariate analyses allow identification of...
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