Article
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
PloS one - 1 Jan 2012
Hart Amy B, Engelhardt Barbara E, Wardle Margaret C, Sokoloff Greta, Stephens Matthew, de Wit Harriet, Palmer Abraham A
Abstract excerpt
Both the subjective response to d-amphetamine and the risk for amphetamine addiction are known to be heritable traits. Because subjective responses to drugs may predict drug addiction, identifying alleles that influence acute response may also provide insight into the genetic risk factors for drug abuse. We performed a Genome Wide Association Study (GWAS) for the subjective responses to amphetamine in 381...
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