Article
Multivariate Analyses Reveal Biological Components Related to Neuronal Signaling and Immunity Mediating Electroencephalograms Abnormalities in Alcohol-Dependent Individuals from the Collaborative Study on the Genetics of Alcoholism Cohort.
Alcoholism, clinical and experimental research - 1 Jul 2019
Meda Shashwath A, Narayanan Balaji, Chorlian David, Meyers Jacquelyn L, Gelernter Joel, Hesselbrock Victor, Bauer Lance, Calhoun Vince D, Porjesz Bernice, Pearlson Godfrey D
Abstract excerpt
BACKGROUND: The underlying molecular mechanisms associated with alcohol use disorder (AUD) risk have only been partially revealed using traditional approaches such as univariate genomewide association and linkage-based analyses. We therefore aimed to identify gene clusters related to Electroencephalograms (EEG) neurobiological phenotypes distinctive to individuals with AUD using a multivariate approach. METHODS:...
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