Beyond structural equation modeling: model properties and effect size from a Bayesian viewpoint. An example of complex phenotype-genotype associations in depression.

Abstract excerpt

Despite the rapid evolution of measurement technologies in biomedicine and genetics, most of the recent studies aiming to explore the genetic background of multifactorial diseases were only moderately successful. One of the causes of this phenomenon is that the bottleneck of genetic research is no longer the measurement process related to various laboratory technologies, but rather the analysis and interpretation...

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