Article
[Frequency of CHEK2 gene mutations in patients with breast cancer from the Republic of Bashkortostan].
Molekuliarnaia biologiia - 1 Jan 2000
Abstract excerpt
Several studies have shown, that mutation in CHEK2 gene can increase the risk of different cancers, including breast cancer (BC). Clearly, that character of mutations distribution in the defined regions is depended on genetic structure of the population. We conducted the screening of mutations c.1100delC, c.444 + 1G>A, de15395, p.I157T andIp.R145Win CHEK2 gene in patients with breast cancer (n = 977) and in...
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