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Article

[Prevalence of mutations BRCA1 5382insC, and CHEK2 1100delC in the population of Siberian region].

Genetika - 1 Jun 2012

Chasovnikova O B, Mitrofanov D V, Anisimenko M S, Voevoda M I, Kovalenko S P, Liakhovich V V

Abstract excerpt

Frequencies of the 538insC mutation in the BRCA1 gene and the 1100delC mutation in the CHEK2 gene were compared in the group of breast cancer patients and the large-scale sample, consisting of 7920 DNA specimens from healthy residents of the city of Novosibirsk. Higher frequencies of these mutations in the patient group compared to the control sample (1.95 versus 0.25% for BRCA1 5382insC, and 1.78 versus 0.40%...

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Source

Identifiers

PMID: 22946335

Genes

BRCA1
CHEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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[Prevalence of mutations BRCA1 5382insC, and CHEK2 1100delC in the population of Siberian region].PMID 22946335Read ↗

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[Ethnic aspects of hereditary breast cancer in the region of Siberia].Semantic proximity Read ↗

Identification of a novel BRCA2 and CHEK2 A-C-G-C haplotype in Turkish patients affected with breast cancer.Semantic proximity Read ↗

CHEK2 1100delC and Del5395bp mutations in BRCA-negative individuals from Serbian hereditary breast and ovarian cancer families.Semantic proximity Read ↗

CHEK2 1100delC mutation is frequent among Russian breast cancer patients.Semantic proximity Read ↗

[Prevalence of widespread BRCA1 gene mutations in patients with familial breast cancer from St. Petersburg].Semantic proximity Read ↗

CHEK2 1100delC variant and breast cancer risk in Caucasians: a meta-analysis based on 25 studies with 29,154 cases and 37,064 controls.Semantic proximity Read ↗

[CHEK2-mutation in Dutch breast cancer families: expanding genetic testing for breast cancer].Semantic proximity Read ↗

CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.Semantic proximity Read ↗

CHEK2 c.1100delC mutation among non-BRCA1/2 Spanish hereditary breast cancer families.Semantic proximity Read ↗

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[Detection of 5382insC mutation in human BRCA1 gene using fluorescent labeled oligonucleotides].Semantic proximity Read ↗

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