Article
HFE gene mutation and oxidative damage biomarkers in patients with myelodysplastic syndromes and its relation to transfusional iron overload: an observational cross-sectional study.
BMJ open - 3 Apr 2015
De Souza Geane Felix, Ribeiro Howard Lopes, De Sousa Juliana Cordeiro, Heredia Fabíola Fernandes, De Freitas Rivelilson Mendes, Martins Manoel Ricardo Alves, Gonçalves Romélia Pinheiro, Pinheiro Ronald Feitosa, Magalhães Silvia Maria Meira
Abstract excerpt
OBJECTIVE: A relation between transfusional IOL (iron overload), HFE status and oxidative damage was evaluated. DESIGN, SETTING AND PARTICIPANTS: An observational cross-sectional study involving 87 healthy individuals and 78 patients with myelodysplastic syndromes (MDS) with and without IOL, seen at University Hospital of the Federal University of Ceará, Brazil, between May 2010 and September 2011. METHODS: IOL...
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