Article
HFE C282Y mutation as a genetic modifier influencing disease susceptibility for chronic myeloproliferative disease.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2009
Andrikovics Hajnalka, Meggyesi Nora, Szilvasi Aniko, Tamaska Julia, Halm Gabriella, Lueff Sandor, Nahajevszky Sarolta, Egyed Miklos, Varkonyi Judit, Mikala Gabor, Sipos Andrea, Kalasz Laszlo, Masszi Tamas, Tordai Attila
Abstract excerpt
Iron metabolism has been implicated in carcinogenesis and several studies assessed the potential role of genetic variants of proteins involved in iron metabolism (HFE C282Y, TFR S142G) in different malignancies. Few reports addressed this issue with relation to chronic myeloproliferative disorders (CMPD). The aims of our study were (a) to examine the potential associations of CMPD development with genetic...
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