Article
Analysis of mitochondrial DNA in 104 patients with myelodysplastic syndromes.
Experimental hematology - 1 May 2008
Wulfert Michael, Küpper Anna C, Tapprich Christoph, Bottomley Sylvia S, Bowen David, Germing Ulrich, Haas Rainer, Gattermann Norbert
Abstract excerpt
OBJECTIVE: To determine the frequency and spectrum of somatic mutations of mitochondrial DNA (mtDNA) in bone marrow of patients with myelodysplastic syndrome (MDS). MATERIALS AND METHODS: Analysis included 104 patients with MDS (24 refractory anemia, 32 refractory anemia with ringed sideroblasts, 34 refractory anemia with excess of blasts, 7 refractory anemia with excess of blasts in transformation to acute...
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