Article
HFE genotype and iron metabolism in Chinese patients with myelodysplastic syndromes and aplastic anemia.
Annals of hematology - 1 Dec 2010
Nie Ling, Li Lin, Yang Lin, Zhang Yue, Xiao Zhijian
Abstract excerpt
The incidence of HFE gene mutations in myelodysplastic syndrome (MDS) cases remains controversial. In this study, we examined the HFE C282Y and H63D mutations in 271 Chinese patients with MDS, 402 with aplastic anemia (AA) and 1,615 healthy controls by polymerase chain reaction-restriction fragment length polymorphism in combination with DNA sequencing. No C282Y mutations were observed in the entire cohort. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.