Article
New aspects of copper and iron metabolism in the myelodysplastic syndromes.
Chemotherapy - 1 Jan 2006
Várkonyi Judit, Szabó Terézia, Sebestyén Piroska, Tordai Attila, Andrikovics Hajnalka, Kollai Géza, Karádi István
Abstract excerpt
BACKGROUND: Myelodysplastic syndrome (MDS) is an iron overload condition. Copper deficiency itself might induce dysplastic changes and iron overload. The relationship between the iron and copper metabolism is analyzed in MDS patients. METHODS: Copper, iron and ceruloplasmin levels were established, and transferrin saturation determination and HFE mutation analysis were performed in 32 MDS patients. RESULTS:...
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