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Article

Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts.

PloS one - 1 Jan 2015

Herrero Laura, Valcarcel Lorea, da Silva Crhistiane Andressa, Albert Nerea, Diez-Noguera Antoni, Cambras Trinitat, Serra Dolors

Abstract excerpt

The circadian clock regulates metabolic homeostasis and its disruption predisposes to obesity and other metabolic diseases. However, the effect of phase shifts on metabolism is not completely understood. We examined whether alterations in the circadian rhythm caused by phase shifts induce metabolic changes in crucial genes that would predispose to obesity. Three-month-old rats were maintained on a standard diet...

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PMID: 25837425
DOI: 10.1371/journal.pone.0122570
PMCID: PMC4383616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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