Article
A rosemary extract enriched in carnosic acid improves circulating adipocytokines and modulates key metabolic sensors in lean Zucker rats: Critical and contrasting differences in the obese genotype.
Molecular nutrition & food research - 1 May 2014
Romo-Vaquero María, Larrosa Mar, Yáñez-Gascón María J, Issaly Nicolas, Flanagan John, Roller Marc, Tomás-Barberán Francisco A, Espín Juan C, García-Conesa María-Teresa
Abstract excerpt
SCOPE: Carnosic acid (CA) and rosemary extracts (REs) have antiobesity effects but the mechanisms are not understood. We investigated some of the potential mechanisms contributing to the metabolic effects of an RE enriched in CA. METHODS AND RESULTS: An RE (∼40% CA) was administered to lean (Le, fa/+) and obese (Ob, fa/fa) female Zucker rats for 64 days. Several adipocytokines, brain-derived neurotrophic factor,...
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