Article
The 164 K, 165 K, and 167 K residues of VP1 are vital for goose parvovirus proliferation in GEFs based on PCR-based reverse genetics system.
Virology journal - 14 Nov 2019
Liu Peng, Yang Liqin, Zhang Jingyue, Wang Tao, Wu Yuanyuan, Wang Mingshu, Jia Renyong, Zhu Dekang, Liu Mafeng, Zhao Xinxin, Yang Qiao, Wu Ying, Zhang Shaqiu, Liu Yunya, Yu Yanling, Zhang Ling, Pan Leichang, Chen Shun, Cheng Anchun
Abstract excerpt
BACKGROUND: Goose parvovirus (GPV) is the etiological agent of Derzsy's disease and is fatal for gosling. Research on the molecular basis of GPV pathogenicity has been hampered by the lack of a reliable reverse genetics system. At present, the GPV infectious clone has been rescued by transfection in the goose embryo, but the growth character of it is unclear in vitro. METHODS: In this study, we identified the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.