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Article

Hypoxia-inducible factor-1α G polymorphism and the risk of cancer: a meta-analysis.

Tumori - 1 Jan 2000

Ye Yanwei, Wang Min, Li Jingjing, Shi Yingqiang, Zhang Xiefu, Zhou Ye, Zhao Chunlin, Wen Jianguo

Abstract excerpt

AIMS AND BACKGROUND: Hypoxia-inducible factor-1α (HIF-1α), a transcription factor, is associated with the initiation and progression of malignant tumors. HIF-1α G (A588T) polymorphism has been shown to lead to genetic susceptibility to malignant tumors but results have been controversial. METHODS AND STUDY DESIGN: We carried out a meta-analysis on 21 eligible case-control studies with a total of 3892 cases and...

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Identifiers

PMID: 25688508
DOI: 10.1700/1778.19290

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