Article
Hypoxia-inducible factor-1α G polymorphism and the risk of cancer: a meta-analysis.
Tumori - 1 Jan 2000
Ye Yanwei, Wang Min, Li Jingjing, Shi Yingqiang, Zhang Xiefu, Zhou Ye, Zhao Chunlin, Wen Jianguo
Abstract excerpt
AIMS AND BACKGROUND: Hypoxia-inducible factor-1α (HIF-1α), a transcription factor, is associated with the initiation and progression of malignant tumors. HIF-1α G (A588T) polymorphism has been shown to lead to genetic susceptibility to malignant tumors but results have been controversial. METHODS AND STUDY DESIGN: We carried out a meta-analysis on 21 eligible case-control studies with a total of 3892 cases and...
Topics
- Asian People
- Digestive System Neoplasms
- Genotype
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit
- Mouth Neoplasms
- Neoplasms
- Odds Ratio
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide
- Publication Bias
- Risk Assessment
- Risk Factors
- White People