Article
Hypoxia-inducible factor-1α rs11549465 C>T and rs11549467 G>A gene polymorphisms are associated with an increased risk of digestive cancers in Asians.
Journal of cancer research and therapeutics - 1 Jan 2018
Wang Wu, Wu Bu-Qiang, Chen Guang-Bin, Zhou Yong, Li Zhao-Hua, Zhang Jian-Liang, Ding Yin-Lu, Zhang Peng, Wang Jin-Qing
Abstract excerpt
OBJECTIVE: We used a meta-analysis framework to examine the correlation between HIF-1α gene polymorphisms and the susceptibility to digestive cancers. METHODS: Cochrane Library Database, EMBASE, MEDLINE, Pubmed, CINAHL, Chinese Biomedical Database and Web of Science were searched without language restrictions to identify relevant case-control studies reporting data on HIF-1α gene polymorphisms in digestive...
Topics
- Alleles
- Asian People
- Digestive System Neoplasms
- Genetic Predisposition to Disease
- Genotype
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit
- Polymorphism, Single Nucleotide
- Population Surveillance
- Risk Assessment
- Risk Factors