Article
Polymorphisms of DNA repair genes in Korean hepatocellular carcinoma patients with chronic hepatitis B: possible implications on survival.
Journal of hepatology - 1 Sept 2012
Jung Seok Won, Park Neung Hwa, Shin Jung Woo, Park Bo Ryung, Kim Chang Jae, Lee Jong-Eun, Shin Eun-Soon, Kim Jeong A, Chung Young-Hwa
Abstract excerpt
BACKGROUND & AIMS: We aimed at determining whether single nucleotide polymorphisms (SNPs) of DNA repair genes influence the development and clinical outcomes of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC). METHODS: We evaluated 14 SNPs of eight DNA repair genes in 708 patients with HCC and 388 HBsAg positive controls without HCC. The Kaplan-Meier methods with log-rank test and Cox regression...
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