Article
Evidence for the role of EPHX2 gene variants in anorexia nervosa.
Molecular psychiatry - 1 Jun 2014
Scott-Van Zeeland A A, Bloss C S, Tewhey R, Bansal V, Torkamani A, Libiger O, Duvvuri V, Wineinger N, Galvez L, Darst B F, Smith E N, Carson A, Pham P, Phillips T, Villarasa N, Tisch R, Zhang G, Levy S, Murray S, Chen W, Srinivasan S, Berenson G, Brandt H, Crawford S, Crow S, Fichter M M, Halmi K A, Johnson C, Kaplan A S, La Via M, Mitchell J E, Strober M, Rotondo A, Treasure J, Woodside D B, Bulik C M, Keel P, Klump K L, Lilenfeld L, Plotnicov K, Topol E J, Shih P B, Magistretti P, Bergen A W, Berrettini W, Kaye W, Schork N J
Abstract excerpt
Anorexia nervosa (AN) and related eating disorders are complex, multifactorial neuropsychiatric conditions with likely rare and common genetic and environmental determinants. To identify genetic variants associated with AN, we pursued a series of sequencing and genotyping studies focusing on the coding regions and upstream sequence of 152 candidate genes in a total of 1205 AN cases and 1948 controls. We...
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