Article
Genome-wide association study identifies common genetic variants associated with salivary gland carcinoma and its subtypes.
Cancer - 15 Jul 2015
Xu Li, Tang Hongwei, Chen Diane W, El-Naggar Adel K, Wei Peng, Sturgis Erich M
Abstract excerpt
BACKGROUND: Salivary gland carcinomas (SGCs) are a rare malignancy with unknown etiology. The objective of the current study was to identify genetic variants modifying the risk of SGC and its major subtypes: adenoid cystic carcinoma and mucoepidermoid carcinoma. METHODS: The authors conducted a genome-wide association study in 309 well-defined SGC cases and 535 cancer-free controls. A single-nucleotide...
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