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Article

Genetic variants in DNA double-strand break repair genes and risk of salivary gland carcinoma: a case-control study.

PloS one - 1 Jan 2015

Xu Li, Tang Hongwei, El-Naggar Adel K, Wei Peng, Sturgis Erich M

Abstract excerpt

DNA double strand break (DSB) repair is the primary defense mechanism against ionizing radiation-induced DNA damage. Ionizing radiation is the only established risk factor for salivary gland carcinoma (SGC). We hypothesized that genetic variants in DSB repair genes contribute to individual variation in susceptibility to SGC. To test this hypothesis, we conducted a case-control study in which we analyzed 415...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26035306
DOI: 10.1371/journal.pone.0128753
PMCID: PMC4452711

Genes

RAD52
XRCC4
PRKDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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