Article
ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure.
American journal of human genetics - 12 Feb 2010
Thornton Timothy, McPeek Mary Sara
Abstract excerpt
Genome-wide association studies are routinely conducted to identify genetic variants that influence complex disorders. It is well known that failure to properly account for population or pedigree structure can lead to spurious association as well as reduced power. We propose a method, ROADTRIPS,...
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