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Article

The feedback control of UPF3 is crucial for RNA surveillance in plants.

Nucleic acids research - 30 Apr 2015

Degtiar Evgeniya, Fridman Adi, Gottlieb Dror, Vexler Karina, Berezin Irina, Farhi Ronit, Golani Linoy, Shaul Orit

Abstract excerpt

Nonsense-mediated-decay (NMD) is a eukaryotic RNA surveillance mechanism that controls the levels of both aberrant and normal transcripts. The regulation of this process is not well understood. The Arabidopsis NMD factor UPF3 is regulated by a negative feedback-loop that targets its own transcript for NMD. We investigated the functional significance of this control for the overall regulation of NMD in...

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Identifiers

PMID: 25820429
DOI: 10.1093/nar/gkv237
PMCID: PMC4417159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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The feedback control of UPF3 is crucial for RNA surveillance in plants.PMID 25820429Read ↗

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UPF3A is dispensable for nonsense-mediated mRNA decay in mouse pluripotent and somatic cellsSemantic proximity Read ↗

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