Article
Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.
Molecular vision - 17 Mar 2008
Aragon-Martin Jose A, Ritch Robert, Liebmann Jeffrey, O'Brien Colm, Blaaow Karima, Mercieca Franco, Spiteri Anthony, Cobb Caroline J, Damji Karim F, Tarkkanen Ahti, Rezaie Tayebeh, Child Anne H, Sarfarazi Mansoor
Abstract excerpt
PURPOSE: To evaluate genetic susceptibility of lysyl oxidase-like 1 (LOXL1) gene polymorphisms to exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) in a case-control cohort of American and European patients. METHODS: DNA from a total of 620 individuals including 287 exfoliation patients and 333 healthy control subjects were extracted by standard methods. Three single nucleotide polymorphisms (SNPs) of...
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