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Article

HDAC inhibitors induce epithelial-mesenchymal transition in colon carcinoma cells.

Oncology reports - 1 May 2015

Ji Meiying, Lee Eun Jeoung, Kim Ki Bae, Kim Yangmi, Sung Rohyun, Lee Sang-Jeon, Kim Don Soo, Park Seon Mee

Abstract excerpt

The effects of histone deacetylase (HDAC) inhibitors on epithelial-mesenchymal transition (EMT) differ in various types of cancers. We investigated the EMT phenotype in four colon cancer cell lines when challenged with HDAC inhibitors trichostatin A (TSA) and valproic acid (VPA) with or without transforming growth factor-β1 (TGF-β1) treatment. Four colon cancer cell lines with different phenotypes in regards to...

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Identifiers

PMID: 25813246
DOI: 10.3892/or.2015.3879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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