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Article

HDAC5 , negatively regulated by miR ‐148a‐3p, promotes colon cancer cell migration

16 May 2022

Abstract excerpt

Histone deacetylases (HDACs) are involved in many processes including tumor cell growth and proliferation and regulation of gene expression. To clarify the role of class IIa HDACs in the metastasis of colon adenocarcinoma, we used the class IIa HDAC inhibitor TMP269 and found that it effectively inhibited the migration ability of colon adenocarcinoma cells. Next, we silenced the member of class IIa HDACs and...

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Share to Epigenetics and DNA Methylation
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PMID: 35574707
DOI: 10.1111/cas.15399

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