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Article

Lifestyle Factors and Microsatellite Instability in Colorectal Cancer: The Evolving Field of Molecular Pathological Epidemiology

5 Mar 2010

Abstract excerpt

Colorectal cancer is not a single disease. It encompasses heterogeneous diseases with different sets of genetic and epigenetic alterations. Each tumor arises and behaves in a unique fashion that is unlikely to be exactly recapitulated by any other tumor ( 1 ). Nevertheless, we classify colorectal cancers into a limited number of groups (eg, microsatellite instability [MSI]-high vs microsatellite stability [MSS])...

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PMID: 20208016
DOI: 10.1093/jnci/djq031

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