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Article

Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors.

Journal of the National Cancer Institute - 15 Nov 2000

Slattery M L, Curtin K, Anderson K, Ma K N, Ballard L, Edwards S, Schaffer D, Potter J, Leppert M, Samowitz W S

Abstract excerpt

BACKGROUND: Microsatellite instability (MSI) has been reported to occur in approximately 10%-15% of colon tumors. MSI is characterized by the presence of mutations in tandemly repeated DNA sequences known as microsatellites. Some individuals with unstable tumors have inherited mutations in mismat...

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PMID: 11078760
DOI: 10.1093/jnci/92.22.1831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11078760-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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